Neutrophil extracellular traps activate IL-8 and IL-1 expression in human bronchial epithelia
نویسندگان
چکیده
منابع مشابه
Mycobacterium tuberculosis- induced neutrophil extracellular traps activate human macrophages.
Neutrophils activated by Mycobacterium tuberculosis (Mtb) form neutrophil extracellular traps (NETs), containing DNA and several biologically active cytosolic and granular proteins. These NETs may assist in the innate immune defense against different pathogens. We investigated whether the NET-forming neutrophils mediate an activating signal to macrophages during the early multicellular inflamma...
متن کاملPar2 Agonists Upregulate G-csf, Il-8 & Vcam-1 Expression in Human Bronchial Fibroblasts
Running Title: PAR 2 induces inflammatory events in fibroblasts. Abstract Proteinase-activated receptors (PARs) are a novel family of G-protein coupled receptors, of which PAR 2 , has been implicated in inflammatory airways disease. Although fibroblasts are pathologically important in the airways, the pro-inflammatory role of PAR 2 in these cells currently remains unknown. Thus, we have assesse...
متن کاملبررسی غلظت IL-1? و IL-6 و IL-8 و TNF-? در کنسانتره های پلاکتی
Background: As increase of cytokines (like IL-1 , IL-6 , IL-8 and TNF- ) in platelet concentrates (PCs) during storage are involved in Febrile Non Hemolytic Transfusion Reactions (FNHTRs) after Platelet transfusion, the aim of this study was the survey of these cytokines level in PCs produced in Tehran Blood Center. Materials and Methods: This study proposed to determine if WBC reduction in P...
متن کاملNeutrophil extracellular traps in bronchial aspirates: a quantitative analysis.
Neutrophil extracellular traps (NETs) are structures composed of DNA and granular proteins, which rapidly trap and kill pathogens. The formation of NETs has been detected during infection in animal experiments, but their role in humans is unclear. The purposes of this study were to quantitatively evaluate the production of NETs during acute respiratory infection and to study the relationship be...
متن کاملExpression of IGF-1, IL-27 and IL-35 Receptors in Adjuvant Induced Rheumatoid Arthritis Model
Background: IGF-1 and certain other cytokines have been shown to exert inflammatory/anti-inflammatory roles in chronic joint diseases. Objective: To assess the effect of IGF-1, IL-27 and IL-35, their interaction and their receptor expression in a rheumatoid arthritis model. Methods: Freund’s adjuvant-induced chronic joint inflammation was operated on 160 male rats. Animals were divided into his...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Physiology-Lung Cellular and Molecular Physiology
سال: 2020
ISSN: 1040-0605,1522-1504
DOI: 10.1152/ajplung.00144.2019